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Transposon debris in ciliate genomes

The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.

Detalles Bibliográficos
Autores principales: Feng, Yi, Landweber, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384191/
https://www.ncbi.nlm.nih.gov/pubmed/34428213
http://dx.doi.org/10.1371/journal.pbio.3001354
Descripción
Sumario:The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.