The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells

Several enveloped viruses, including herpesviruses attach to host cells by initially interacting with cell surface heparan sulfate (HS) proteoglycans followed by specific coreceptor engagement which culminates in virus-host membrane fusion and virus entry. Interfering with HS-herpesvirus interaction...

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Detalles Bibliográficos
Autores principales: Mitra, Dipanwita, Hasan, Mohammad H., Bates, John T., Bierdeman, Michael A., Ederer, Dallas R., Parmar, Rinkuben C., Fassero, Lauren A., Liang, Quntao, Qiu, Hong, Tiwari, Vaibhav, Zhang, Fuming, Linhardt, Robert J., Sharp, Joshua S., Wang, Lianchun, Tandon, Ritesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384199/
https://www.ncbi.nlm.nih.gov/pubmed/34352038
http://dx.doi.org/10.1371/journal.ppat.1009803

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