Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review

Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but...

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Autores principales: Atolagbe, Ayodele, Nkemjika, Stanley, Popoola, Olusegun, Oladeji, Oluwatoyin, Kogan, Irina, Saeed, Haroon, Olupona, Tolulope
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384506/
https://www.ncbi.nlm.nih.gov/pubmed/34447597
http://dx.doi.org/10.1155/2021/3980872
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author Atolagbe, Ayodele
Nkemjika, Stanley
Popoola, Olusegun
Oladeji, Oluwatoyin
Kogan, Irina
Saeed, Haroon
Olupona, Tolulope
author_facet Atolagbe, Ayodele
Nkemjika, Stanley
Popoola, Olusegun
Oladeji, Oluwatoyin
Kogan, Irina
Saeed, Haroon
Olupona, Tolulope
author_sort Atolagbe, Ayodele
collection PubMed
description Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol.
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spelling pubmed-83845062021-08-25 Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review Atolagbe, Ayodele Nkemjika, Stanley Popoola, Olusegun Oladeji, Oluwatoyin Kogan, Irina Saeed, Haroon Olupona, Tolulope Case Rep Psychiatry Case Report Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol. Hindawi 2021-08-17 /pmc/articles/PMC8384506/ /pubmed/34447597 http://dx.doi.org/10.1155/2021/3980872 Text en Copyright © 2021 Ayodele Atolagbe et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Atolagbe, Ayodele
Nkemjika, Stanley
Popoola, Olusegun
Oladeji, Oluwatoyin
Kogan, Irina
Saeed, Haroon
Olupona, Tolulope
Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_full Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_fullStr Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_full_unstemmed Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_short Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_sort risperidone-induced neutropenia in a schizophrenic patient: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384506/
https://www.ncbi.nlm.nih.gov/pubmed/34447597
http://dx.doi.org/10.1155/2021/3980872
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