Cargando…
Functional genomics for breast cancer drug target discovery
Breast cancer is a heterogeneous disease that develops through a multistep process via the accumulation of genetic/epigenetic alterations in various cancer-related genes. Current treatment options for breast cancer patients include surgery, radiotherapy, and chemotherapy including conventional cytot...
Autores principales: | Yoshimaru, Tetsuro, Nakamura, Yusuke, Katagiri, Toyomasa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384626/ https://www.ncbi.nlm.nih.gov/pubmed/34285339 http://dx.doi.org/10.1038/s10038-021-00962-6 |
Ejemplares similares
-
Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer
por: Yoshimaru, Tetsuro, et al.
Publicado: (2015) -
Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells
por: Yoshimaru, Tetsuro, et al.
Publicado: (2013) -
Infrequent Mutation of the H‐Cadherin Gene on Chromosome 16q24 in Human Breast Cancers
por: Miki, Yoshio, et al.
Publicado: (1997) -
Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions
por: Yoshimaru, Tetsuro, et al.
Publicado: (2014) -
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure
por: Chen, Yi-An, et al.
Publicado: (2014)