A five amino acids deletion in NKCC2 of C57BL/6 mice affects analysis of NKCC2 phosphorylation but does not impact kidney function

AIM: The phosphorylation level of the furosemide‐sensitive Na(+)‐K(+)‐2Cl(−) cotransporter (NKCC2) in the thick ascending limb (TAL) is used as a surrogate marker for NKCC2 activation and TAL function. However, in mice, analyses of NKCC2 phosphorylation with antibodies against phosphorylated threoni...

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Detalles Bibliográficos
Autores principales: Moser, Sandra, Sugano, Yuya, Wengi, Agnieszka, Fisi, Viktoria, Lindtoft Rosenbaek, Lena, Mariniello, Marta, Loffing‐Cueni, Dominique, McCormick, James A., Fenton, Robert A., Loffing, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Renal Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384713/
https://www.ncbi.nlm.nih.gov/pubmed/34114742
http://dx.doi.org/10.1111/apha.13705

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