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Estrogen augmented visceral pain and colonic neuron modulation in a double-hit model of prenatal and adult stress
BACKGROUND: Chronic stress during pregnancy may increase visceral hyperalgesia of offspring in a sex-dependent way. Combining adult stress in offspring will increase this sensitivity. Based on the evidence implicating estrogen in exacerbating visceral hypersensitivity in female rodents in preclinica...
Autores principales: | Chen, Jing-Hong, Sun, Ying, Ju, Pei-Jun, Wei, Jin-Bao, Li, Qing-Jie, Winston, John H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384739/ https://www.ncbi.nlm.nih.gov/pubmed/34497435 http://dx.doi.org/10.3748/wjg.v27.i30.5060 |
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