Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophages in patients with critical COVID-19

Understanding host cell heterogeneity is critical for unraveling disease mechanism. Utilizing large-scale single-cell transcriptomics, we analyzed multiple tissue specimens from patients with life-threatening COVID-19 pneumonia, compared with healthy controls. We identified a subtype of monocyte-der...

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Detalles Bibliográficos
Autores principales: Nassir, Nasna, Tambi, Richa, Bankapur, Asma, Al Heialy, Saba, Karuvantevida, Noushad, Khansaheb, Hamda Hassan, Zehra, Binte, Begum, Ghausia, Hameid, Reem Abdel, Ahmed, Awab, Deesi, Zulfa, Alkhajeh, Abdulmajeed, Uddin, K.M. Furkan, Akter, Hosneara, Safizadeh Shabestari, Seyed Ali, Almidani, Omar, Islam, Amirul, Gaudet, Mellissa, Kandasamy, Richard Kumaran, Loney, Tom, Tayoun, Ahmad Abou, Nowotny, Norbert, Woodbury-Smith, Marc, Rahman, Proton, Kuebler, Wolfgang M., Yaseen Hachim, Mahmood, Casanova, Jean-Laurent, Berdiev, Bakhrom K., Alsheikh-Ali, Alawi, Uddin, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384759/
https://www.ncbi.nlm.nih.gov/pubmed/34458692
http://dx.doi.org/10.1016/j.isci.2021.103030

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