Reproducibility and robustness of high-throughput S1500+ transcriptomics on primary rat hepatocytes for chemical-induced hepatotoxicity assessment()

Cell-based in vitro models coupled with high-throughput transcriptomics (HTTr) are increasingly utilized as alternative methods to animal-based toxicity testing. Here, using a panel of 14 chemicals with different risks of human drug-induced liver injury (DILI) and two dosing concentrations, we evalu...

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Detalles Bibliográficos
Autores principales: Lee, Fan, Shah, Imran, Soong, Yun Ting, Xing, Jiangwa, Ng, Inn Chuan, Tasnim, Farah, Yu, Hanry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384775/
https://www.ncbi.nlm.nih.gov/pubmed/34467220
http://dx.doi.org/10.1016/j.crtox.2021.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384775/
https://www.ncbi.nlm.nih.gov/pubmed/34467220
http://dx.doi.org/10.1016/j.crtox.2021.07.003

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