Absence of QTc Prolongation with Sodium N-(8-[2-Hydroxybenzoyl] Amino) Caprylate (SNAC), an Absorption Enhancer Co-Formulated with the GLP-1 Analogue Semaglutide for Oral Administration

INTRODUCTION: Oral delivery of proteins, including glucagon-like peptide 1 (GLP-1) receptor agonists, is impeded by low gastrointestinal permeation. Oral semaglutide has been developed for once-daily oral administration by co-formulation of the GLP-1 analogue semaglutide with an absorption enhancer,...

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Detalles Bibliográficos
Autores principales: Granhall, Charlotte, Bækdal, Tine A., Breitschaft, Astrid, Søndergaard, Flemming L., Anderson, Thomas W., Thomsen, Mette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384972/
https://www.ncbi.nlm.nih.gov/pubmed/34319564
http://dx.doi.org/10.1007/s13300-021-01106-x

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