Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

Ten-eleven translocation (TET) proteins, the dioxygenase for DNA hydroxymethylation, are important players in nervous system development and diseases. However, their role in myelination and remyelination after injury remains elusive. Here, we identify a genome-wide and locus-specific DNA hydroxymeth...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Wang, Jian, Zhang, Kaixiang, Lu, Guozhen, Liu, Yuming, Ren, Keke, Wang, Wenting, Xin, Dazhuan, Xu, Lingli, Mao, Honghui, Xing, Junlin, Gao, Xingchun, Jin, Weilin, Berry, Kalen, Mikoshiba, Katsuhiko, Wu, Shengxi, Lu, Q. Richard, Zhao, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385008/
https://www.ncbi.nlm.nih.gov/pubmed/34429415
http://dx.doi.org/10.1038/s41467-021-25353-5

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