Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn(2+) ions

Toll-like receptors (TLRs) play an important role in the innate immune response. While a lot is known about the structures of their extracellular parts, many questions are still left unanswered, when the structural basis of TLR activation is analyzed for the TLR intracellular domains. Here we report...

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Detalles Bibliográficos
Autores principales: Lushpa, Vladislav A., Goncharuk, Marina V., Lin, Cong, Zalevsky, Arthur O., Talyzina, Irina A., Luginina, Aleksandra P., Vakhrameev, Daniil D., Shevtsov, Mikhail B., Goncharuk, Sergey A., Arseniev, Alexander S., Borshchevskiy, Valentin I., Wang, Xiaohui, Mineev, Konstantin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385042/
https://www.ncbi.nlm.nih.gov/pubmed/34429510
http://dx.doi.org/10.1038/s42003-021-02532-0

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