Soluble trivalent engagers redirect cytolytic T cell activity toward tumor endothelial marker 1

Tumor endothelial marker 1 (TEM1) is an emerging cancer target with a unique dual expression profile. First, TEM1 is expressed in the stroma and neo-vasculature of many human carcinomas but is largely absent from healthy adult tissues. Second, TEM1 is expressed by tumor cells of mesenchymal origin,...

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Detalles Bibliográficos
Autores principales: Fierle, Julie K., Brioschi, Matteo, de Tiani, Mariastella, Wetterwald, Laureline, Atsaves, Vasileios, Abram-Saliba, Johan, Petrova, Tatiana V., Coukos, George, Dunn, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385295/
https://www.ncbi.nlm.nih.gov/pubmed/34467246
http://dx.doi.org/10.1016/j.xcrm.2021.100362

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