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Elevated glucose increases genomic instability by inhibiting nucleotide excision repair

We investigated potential mechanisms by which elevated glucose may promote genomic instability. Gene expression studies, protein measurements, mass spectroscopic analyses, and functional assays revealed that elevated glucose inhibited the nucleotide excision repair (NER) pathway, promoted DNA strand...

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Detalles Bibliográficos
Autores principales:	Ciminera, Alexandra K, Shuck, Sarah C, Termini, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385305/ https://www.ncbi.nlm.nih.gov/pubmed/34426491 http://dx.doi.org/10.26508/lsa.202101159

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