A protein regulated by UBE3A PEGs a potential biomarker

New research from Pandya and colleagues(1) identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development.

Detalles Bibliográficos
Autores principales: Germain, Noelle D., Chamberlain, Stormy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385320/
https://www.ncbi.nlm.nih.gov/pubmed/34467252
http://dx.doi.org/10.1016/j.xcrm.2021.100377
Descripción
Sumario:New research from Pandya and colleagues(1) identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development.

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