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A protein regulated by UBE3A PEGs a potential biomarker
New research from Pandya and colleagues(1) identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385320/ https://www.ncbi.nlm.nih.gov/pubmed/34467252 http://dx.doi.org/10.1016/j.xcrm.2021.100377 |
| _version_ | 1783742070096134144 |
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| author | Germain, Noelle D. Chamberlain, Stormy J. |
| author_facet | Germain, Noelle D. Chamberlain, Stormy J. |
| author_sort | Germain, Noelle D. |
| collection | PubMed |
| description | New research from Pandya and colleagues(1) identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development. |
| format | Online Article Text |
| id | pubmed-8385320 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-83853202021-08-30 A protein regulated by UBE3A PEGs a potential biomarker Germain, Noelle D. Chamberlain, Stormy J. Cell Rep Med Preview New research from Pandya and colleagues(1) identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development. Elsevier 2021-08-17 /pmc/articles/PMC8385320/ /pubmed/34467252 http://dx.doi.org/10.1016/j.xcrm.2021.100377 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Preview Germain, Noelle D. Chamberlain, Stormy J. A protein regulated by UBE3A PEGs a potential biomarker |
| title | A protein regulated by UBE3A PEGs a potential biomarker |
| title_full | A protein regulated by UBE3A PEGs a potential biomarker |
| title_fullStr | A protein regulated by UBE3A PEGs a potential biomarker |
| title_full_unstemmed | A protein regulated by UBE3A PEGs a potential biomarker |
| title_short | A protein regulated by UBE3A PEGs a potential biomarker |
| title_sort | protein regulated by ube3a pegs a potential biomarker |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385320/ https://www.ncbi.nlm.nih.gov/pubmed/34467252 http://dx.doi.org/10.1016/j.xcrm.2021.100377 |
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