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Localization of enteroviral RNA within the pancreas in donors with T1D and T1D-associated autoantibodies
Enteroviral infections have been associated with autoimmunity and type 1 diabetes (T1D), but reliable methods to ascertain localization of single infected cells in the pancreas were missing. Using a single-molecule-based fluorescent in situ hybridization (smFISH) method, we detected increased virus...
Autores principales: | Geravandi, Shirin, Richardson, Sarah, Pugliese, Alberto, Maedler, Kathrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385321/ https://www.ncbi.nlm.nih.gov/pubmed/34467248 http://dx.doi.org/10.1016/j.xcrm.2021.100371 |
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