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A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice

Although the BCG vaccine offers partial protection, tuberculosis remains a leading cause of infectious disease death, killing ∼1.5 million people annually. We developed mucosal vaccines expressing the autophagy-inducing peptide C5 and mycobacterial Ag85B-p25 epitope using replication-defective human...

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Detalles Bibliográficos
Autores principales:	Khan, Arshad, Sayedahmed, Ekramy E., Singh, Vipul K., Mishra, Abhishek, Dorta-Estremera, Stephanie, Nookala, Sita, Canaday, David H., Chen, Min, Wang, Jin, Sastry, K. Jagannadha, Mittal, Suresh K., Jagannath, Chinnaswamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385328/ https://www.ncbi.nlm.nih.gov/pubmed/34467249 http://dx.doi.org/10.1016/j.xcrm.2021.100372

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