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Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment
In response to DNA damage, efficient repair is essential for cell survival and genome integrity. In eukaryotes, the DNA damage checkpoint is a signalling pathway that coordinates this response and arrests the cell cycle to provide time for repair. However, when repair fails or when the damage is not...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385375/ https://www.ncbi.nlm.nih.gov/pubmed/34457341 http://dx.doi.org/10.1098/rsos.210460 |