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Plasma Neurofilament Light and Future Declines in Cognition and Function in Alzheimer’s Disease in the FIT-AD Trial

BACKGROUND: Utilities of blood-based biomarkers in Alzheimer’s disease (AD) clinical trials remain unknown. OBJECTIVE: To evaluate the ability of plasma neurofilament light chain (NfL) to predict future declines in cognition and activities of daily living (ADL) outcomes in 26 older adults with mild-...

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Detalles Bibliográficos
Autores principales: Li, Danni, Zhang, Lin, Nelson, Nathaniel W., Mielke, Michelle M., Yu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385429/
https://www.ncbi.nlm.nih.gov/pubmed/34514342
http://dx.doi.org/10.3233/ADR-210302