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Mouse Model of Loeys–Dietz Syndrome Shows Elevated Susceptibility to Periodontitis via Alterations in Transforming Growth Factor-Beta Signaling

Loeys–Dietz syndrome (LDS) is a syndromic connective tissue disorder caused by a heterozygous missense mutation in genes that encode transforming growth factor (TGF)-β receptor (TGFBR) 1 and 2. We encountered a patient with LDS, who had severe periodontal tissue destruction indicative of aggressive...

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Detalles Bibliográficos
Autores principales:	Yamada, Satoru, Tsushima, Kenichiro, Kinoshita, Masaki, Sakashita, Hiromi, Kajikawa, Tetsuhiro, Fujihara, Chiharu, Yuan, Hang, Suzuki, Shigeki, Morisaki, Takayuki, Murakami, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385443/ https://www.ncbi.nlm.nih.gov/pubmed/34456753 http://dx.doi.org/10.3389/fphys.2021.715687

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