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m(6)A Methyltransferase METTL14-Mediated Upregulation of Cytidine Deaminase Promoting Gemcitabine Resistance in Pancreatic Cancer

OBJECTIVE: Pancreatic cancer is one of the most lethal human malignancies. Gemcitabine is widely used to treat pancreatic cancer, and the resistance to chemotherapy is the major difficulty in treating the disease. N (6)-methyladenosine (m(6)A) modification, which regulates RNA splicing, stability, t...

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Detalles Bibliográficos
Autores principales:	Zhang, Congjun, Ou, Shuangyan, Zhou, Yuan, Liu, Pei, Zhang, Peiying, Li, Ziqian, Xu, Ruocai, Li, Yuqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385558/ https://www.ncbi.nlm.nih.gov/pubmed/34458141 http://dx.doi.org/10.3389/fonc.2021.696371

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