Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis

BACKGROUND: Macrophages are pivotal cells in sarcoidosis. Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. From inflammatory tissues to granulomas, they may be exposed to low oxygen tension environments. As hypoxia impact on...

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Detalles Bibliográficos
Autores principales: Jeny, Florence, Bernaudin, Jean-François, Valeyre, Dominique, Kambouchner, Marianne, Pretolani, Marina, Nunes, Hilario, Planès, Carole, Besnard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385772/
https://www.ncbi.nlm.nih.gov/pubmed/34456926
http://dx.doi.org/10.3389/fimmu.2021.719009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385772/
https://www.ncbi.nlm.nih.gov/pubmed/34456926
http://dx.doi.org/10.3389/fimmu.2021.719009

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