Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

BACKGROUND: Genome-wide association studies have reported more than 100 risk loci for rheumatoid arthritis (RA). These loci are shown to be enriched in immune cell-specific enhancers, but the analysis so far has excluded stromal cells, such as synovial fibroblasts (FLS), despite their crucial involv...

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Detalles Bibliográficos
Autores principales: Ge, Xiangyu, Frank-Bertoncelj, Mojca, Klein, Kerstin, McGovern, Amanda, Kuret, Tadeja, Houtman, Miranda, Burja, Blaž, Micheroli, Raphael, Shi, Chenfu, Marks, Miriam, Filer, Andrew, Buckley, Christopher D., Orozco, Gisela, Distler, Oliver, Morris, Andrew P., Martin, Paul, Eyre, Stephen, Ospelt, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385949/
https://www.ncbi.nlm.nih.gov/pubmed/34433485
http://dx.doi.org/10.1186/s13059-021-02460-6

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