Long non-coding RNA TUG1 knockdown promotes autophagy and improves acute renal injury in ischemia-reperfusion-treated rats by binding to microRNA-29 to silence PTEN

OBJECTIVE: Long noncoding RNA (lncRNA) taurine upregulated gene 1 (TUG1) is increased under the condition of ischemia. This study intended to identify the mechanism of TUG1 in renal ischemia-reperfusion (I/R). METHODS: First, a rat model of acute renal injury induced by I/R was established, followed...

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Detalles Bibliográficos
Autores principales: Xu, Zhiquan, Huang, Xiaoyan, Lin, Qiuyu, Xiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385981/
https://www.ncbi.nlm.nih.gov/pubmed/34429073
http://dx.doi.org/10.1186/s12882-021-02473-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385981/
https://www.ncbi.nlm.nih.gov/pubmed/34429073
http://dx.doi.org/10.1186/s12882-021-02473-0

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