Different Aspects of Classical Pathway Overactivation in Patients With C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis

The rare and heterogeneous kidney disorder C3 glomerulopathy (C3G) is characterized by dysregulation of the alternative pathway (AP) of the complement system. C3G is often associated with autoantibodies stabilizing the AP C3 convertase named C3 nephritic factors (C3NeF). The role of classical pathwa...

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Detalles Bibliográficos
Autores principales: Michels, Marloes A. H. M., van de Kar, Nicole C. A. J., van Kraaij, Sanne A. W., Sarlea, Sebastian A., Gracchi, Valentina, Engels, Flore A. P. T., Dorresteijn, Eiske M., van der Deure, Johannes, Duineveld, Caroline, Wetzels, Jack F. M., van den Heuvel, Lambertus P. W. J., Volokhina, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386118/
https://www.ncbi.nlm.nih.gov/pubmed/34456924
http://dx.doi.org/10.3389/fimmu.2021.715704

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