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TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage

Increasing evidence suggests that triggering receptor expressed on myeloid cells 2 (TREM2) is implicated in the pathophysiology of neuroinflammation. The aim here was to investigate the neuroprotective role of TREM2 and its regulatory mechanism after subarachnoid hemorrhage (SAH). TREM2 siRNA was ad...

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Detalles Bibliográficos
Autores principales: Hu, Yangchun, Li, Chao, Wang, Xiaojian, Chen, Weiwei, Qian, Yu, Dai, Xingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386127/
https://www.ncbi.nlm.nih.gov/pubmed/34458257
http://dx.doi.org/10.3389/fcell.2021.693342