Collagen matrix membrane as a biological dressing in defects of the oral mucosa

OBJECTIVES: The objectives of this study were to evaluate the usefulness of the extracellular collagen matrix membrane as a biological wound dressing material for defects of the oral mucosa. MATERIALS AND METHODS: One hundred two patients were included in the study. A bovine-based extracellular matrix collagen membrane was used. The study was confined to those defects of oral mucosa which were large enough to close primarily. RESULTS: The results were evaluated under various parameters such as hemostasis, pain relief, granulation, epithelialization, and contracture of the wound. Secondary infection and allergenicity to the membrane were also considered, and finally, the usefulness of the collagen membrane was tested by the use of the Chi-square test and P < 0.001 was found. CONCLUSION: We concluded that the extracellular collagen membrane could be used as a biological dressing in oral defects. Although it does not replace, it is proved as a good substitute of autologous graft.