Cargando…

Multidimensional Clinical Surveillance of Pseudomonas aeruginosa Reveals Complex Relationships between Isolate Source, Morphology, and Antimicrobial Resistance

Antimicrobial susceptibility in Pseudomonas aeruginosa is dependent on a complex combination of host and pathogen-specific factors. Through the profiling of 971 clinical P. aeruginosa isolates from 590 patients and collection of paired patient metadata, we show that antimicrobial resistance is assoc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dunphy, Laura J., Kolling, Glynis L., Jenior, Matthew L., Carroll, Joanne, Attai, April E., Farnoud, Farzad, Mathers, Amy J., Hughes, Molly A., Papin, Jason A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386403/ https://www.ncbi.nlm.nih.gov/pubmed/34259555 http://dx.doi.org/10.1128/mSphere.00393-21

Ejemplares similares

Untargeted Metabolomics Reveals Species-Specific Metabolite Production and Shared Nutrient Consumption by Pseudomonas aeruginosa and Staphylococcus aureus
por: Dunphy, Laura J., et al.
Publicado: (2021)

Network analysis of toxin production in Clostridioides difficile identifies key metabolic dependencies
por: Powers, Deborah A., et al.
Publicado: (2023)

Model-driven characterization of functional diversity of Pseudomonas aeruginosa clinical isolates with broadly representative phenotypes
por: Islam, Mohammad Mazharul, et al.
Publicado: (2023)

Some like it hot: Variable impact of a tailpiece heating device on different gram-negative bacteria
por: Park, Stacy, et al.
Publicado: (2023)

An updated genome-scale metabolic network reconstruction of Pseudomonas aeruginosa PA14 to characterize mucin-driven shifts in bacterial metabolism
por: Payne, Dawson D., et al.
Publicado: (2021)

Pseudomonas aeruginosa reverse diauxie is a multidimensional, optimized, resource utilization strategy
por: McGill, S. Lee, et al.
Publicado: (2021)

Novel Multiscale Modeling Tool Applied to Pseudomonas aeruginosa Biofilm Formation
por: Biggs, Matthew B., et al.
Publicado: (2013)

Genomic surveillance of Pseudomonas aeruginosa in the Philippines, 2013–2014
por: Chilam, Jeremiah, et al.
Publicado: (2021)

Genome-scale metabolic modeling reveals increased reliance on valine catabolism in clinical isolates of Klebsiella pneumoniae
por: Jenior, Matthew L., et al.
Publicado: (2022)

Reconstructor: a COBRApy compatible tool for automated genome-scale metabolic network reconstruction with parsimonious flux-based gap-filling
por: Jenior, Matthew L, et al.
Publicado: (2023)

Segregation but Not Replication of the Pseudomonas aeruginosa Chromosome Terminates at Dif
por: Bhowmik, Bijit K., et al.
Publicado: (2018)

Novel co-culture plate enables growth dynamic-based assessment of contact-independent microbial interactions
por: Moutinho, Thomas J., et al.
Publicado: (2017)

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis
por: Bartell, Jennifer A., et al.
Publicado: (2017)

Morphological and Bactericidal Effects of Amikacin, Meropenem and Imipenem on Pseudomonas aeruginosa
por: Moghoofei, Mohsen, et al.
Publicado: (2015)

Mathematical modelling of the antibiotic-induced morphological transition of Pseudomonas aeruginosa
por: Spalding, Chloe, et al.
Publicado: (2018)

Subversion of Mucosal Barrier Polarity by Pseudomonas Aeruginosa
por: Engel, Joanne, et al.
Publicado: (2011)

Transcriptome-guided parsimonious flux analysis improves predictions with metabolic networks in complex environments
por: Jenior, Matthew L., et al.
Publicado: (2020)

Quantifying cumulative phenotypic and genomic evidence for procedural generation of metabolic network reconstructions
por: Moutinho, Thomas J., et al.
Publicado: (2022)

Systems-level metabolism of the altered Schaedler flora, a complete gut microbiota
por: Biggs, Matthew B, et al.
Publicado: (2017)

A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa
por: Tjahjono, Elissa, et al.
Publicado: (2017)

Surveillance of bacteria Pseudomonas aeruginosa and MRSA associated with chronic suppurative otitis media()
por: Rath, Sibanarayan, et al.
Publicado: (2016)

Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype(1)(2)
por: Mayneris-Perxachs, Jordi, et al.
Publicado: (2016)

90. Impact of Discrepant Rapid Diagnostic Test (RDT) Results on Antimicrobial Stewardship Program (ASP) Interventions in Patients with Bloodstream Infections (BSI) due to Gram-Negative Bacilli (GNB)
por: Robinson, Evan D, et al.
Publicado: (2020)

Multidrug Resistant Pseudomonas aeruginosa in Iran: A Systematic Review and Metaanalysis
por: Vaez, Hamid, et al.
Publicado: (2018)

Fitness of Isogenic Colony Morphology Variants of Pseudomonas aeruginosa in Murine Airway Infection
por: Rakhimova, Elza, et al.
Publicado: (2008)

Quorum sensing modulates colony morphology through alkyl quinolones in Pseudomonas aeruginosa
por: Gupta, Rashmi, et al.
Publicado: (2012)

394. Pseudo-outbreak of Coagulase-negative Staphylococcus Species from Blood Cultures Highlights Unique Challenges in Care of Critically Ill Patients With COVID-19
por: Park, Stacy, et al.
Publicado: (2020)

Synthesis and Evaluation of Pseudomonas aeruginosa ATP Synthase Inhibitors
por: Ciprich, John F., et al.
Publicado: (2022)

Resistance of Pseudomonas Aeruginosa
por: Graevenitz, Alexander Von
Publicado: (1977)

Pseudomonas aeruginosa Biofilms
por: Thi, Minh Tam Tran, et al.
Publicado: (2020)

Enteric pathogens through life stages
por: Kolling, Glynis, et al.
Publicado: (2012)

Molecular surveillance of carbapenemase-producing Pseudomonas aeruginosa at three medical centres in Cologne, Germany
por: Schäfer, Elena, et al.
Publicado: (2019)

The prevalence of Pseudomonas aeruginosa and multidrug resistant Pseudomonas aeruginosa in healthy captive ophidian
por: Sala, Andrea, et al.
Publicado: (2019)

Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions
por: Blais, Edik M., et al.
Publicado: (2017)

The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology
por: Wood, Thomas E., et al.
Publicado: (2019)

Mechanotaxis directs Pseudomonas aeruginosa twitching motility
por: Kühn, Marco J., et al.
Publicado: (2021)

The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung
por: O'Brien, Siobhán, et al.
Publicado: (2017)

Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary Hepatocytes
por: Rawls, Kristopher D, et al.
Publicado: (2019)

2143. Attempting to Add Clarity to “Indeterminates” on a Deployed Rapid Diagnostic with Antimicrobial Stewardship Program (ASP) Intervention
por: Cox, Heather L, et al.
Publicado: (2019)

FimL Regulates cAMP Synthesis in Pseudomonas aeruginosa
por: Inclan, Yuki F., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9qqv4m81giokq3gd9kbie2jsjv