The effect of PEGylation on the efficacy and uptake of an immunostimulatory nanoparticle in the tumor immune microenvironment

The efficacy of immunotherapies is often limited by the immunosuppressive tumor microenvironment, which is populated with dysfunctional innate immune cells. To reprogram the tumor-resident innate immune cells, we developed immunostimulatory silica mesoporous nanoparticles (immuno-MSN). The cargo of...

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Detalles Bibliográficos
Autores principales: Becicka, Wyatt M., Bielecki, Peter A., Lorkowski, Morgan E., Moon, Taylor J., Zhang, Yahan, Atukorale, Prabhani U., Covarrubias, Gil, Karathanasis, Efstathios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386411/
https://www.ncbi.nlm.nih.gov/pubmed/34485818
http://dx.doi.org/10.1039/d1na00308a

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