Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), harboring spike protein N-terminal domain (NTD) or receptor-binding domain (RBD) mutations, exhibit reduced in vitro susceptibility to convalescent-phase serum, commercial antibody cocktails, and vaccine neutral...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Zody, Michael C., Di Germanio, Clara, Martinelli, Rachel, Mediavilla, Jose R., Cunningham, Marcus H., Composto, Kaelea, Chow, Kar Fai, Kordalewska, Milena, Corvelo, André, Oschwald, Dayna M., Fennessey, Samantha, Zetkulic, Marygrace, Dar, Sophia, Kramer, Yael, Mathema, Barun, Germer, Soren, Stone, Mars, Simmons, Graham, Busch, Michael P., Maniatis, Tom, Perlin, David S., Kreiswirth, Barry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386433/
https://www.ncbi.nlm.nih.gov/pubmed/34431691
http://dx.doi.org/10.1128/mSphere.00480-21

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