Cargando…

A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917

The probiotic Escherichia coli strain Nissle 1917 (DSM 6601, Mutaflor), generally considered beneficial and safe, has been used for a century to treat various intestinal diseases. However, Nissle 1917 hosts in its genome the pks pathogenicity island that codes for the biosynthesis of the genotoxin c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nougayrède, Jean-Philippe, Chagneau, Camille V., Motta, Jean-Paul, Bossuet-Greif, Nadège, Belloy, Marcy, Taieb, Frédéric, Gratadoux, Jean-Jacques, Thomas, Muriel, Langella, Philippe, Oswald, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386472/ https://www.ncbi.nlm.nih.gov/pubmed/34378987 http://dx.doi.org/10.1128/mSphere.00624-21

Ejemplares similares

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917
por: Massip, Clémence, et al.
Publicado: (2019)

Genotoxicity of Escherichia coli Nissle 1917 strain cannot be dissociated from its probiotic activity
por: Olier, Maïwenn, et al.
Publicado: (2012)

The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin
por: Tang-Fichaux, Min, et al.
Publicado: (2020)

The Carbon Storage Regulator (Csr) System Exerts a Nutrient-Specific Control over Central Metabolism in Escherichia coli Strain Nissle 1917
por: Revelles, Olga, et al.
Publicado: (2013)

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells
por: Bossuet-Greif, Nadège, et al.
Publicado: (2018)

The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin
por: Chagneau, Camille V., et al.
Publicado: (2019)

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population
por: Auvray, Frédéric, et al.
Publicado: (2021)

Oxygen concentration modulates colibactin production
por: Bossuet, Nadège, et al.
Publicado: (2023)

No Genotoxicity Is Detectable for Escherichia coli Strain Nissle 1917 by Standard In Vitro and In Vivo Tests
por: Dubbert, Silke, et al.
Publicado: (2020)

Uropathogenic E. coli induces DNA damage in the bladder
por: Chagneau, Camille V., et al.
Publicado: (2021)

Reply to Dubbert and von Bünau, “A Probiotic Friend”
por: Nougayrède, Jean-Philippe, et al.
Publicado: (2021)

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917
por: Pérez-Berezo, Teresa, et al.
Publicado: (2017)

Uncoupling the Hsp90 and DnaK chaperone activities revealed the in vivo relevance of their collaboration in bacteria
por: Corteggiani, Marie, et al.
Publicado: (2022)

Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells
por: Taieb, Frédéric, et al.
Publicado: (2011)

E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells
por: Schierack, Peter, et al.
Publicado: (2011)

Bioengineered Escherichia coli Nissle 1917 for tumour‐targeting therapy
por: Yu, Xiaoli, et al.
Publicado: (2019)

Mutagenic and Genotoxic Effect of Hydroxyurea
por: Santos, Jean L., et al.
Publicado: (2011)

Gradient Magnetic Field Accelerates Division of E. coli Nissle 1917
por: Gorobets, Svitlana, et al.
Publicado: (2023)

Escherichiacoli Nissle 1917 as a Novel Microrobot for Tumor-Targeted Imaging and Therapy
por: Liu, Qingyao, et al.
Publicado: (2021)

Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity
por: Ukena, Sya N., et al.
Publicado: (2007)

The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ
por: Bury, Susanne, et al.
Publicado: (2018)

The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice
por: Rodríguez-Nogales, Alba, et al.
Publicado: (2018)

Engineered E. coli Nissle 1917 for the reduction of vancomycin‐resistant Enterococcus in the intestinal tract
por: Geldart, Kathryn G., et al.
Publicado: (2018)

Effects of Escherichia coli strain Nissle 1917 on exercise-induced disruption of gastrointestinal integrity
por: Mooren, F. C., et al.
Publicado: (2020)

Transcriptional Profiling of the Probiotic Escherichia coli Nissle 1917 Strain under Simulated Microgravity
por: Yim, Jaewoo, et al.
Publicado: (2020)

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
por: Praveschotinunt, Pichet, et al.
Publicado: (2019)

Anti-inflammatory properties of Escherichia coli Nissle 1917 in a murine colitis model
por: Park, Jihye, et al.
Publicado: (2021)

Plasmid Vectors for in Vivo Selection-Free Use with the Probiotic E. coli Nissle 1917
por: Kan, Anton, et al.
Publicado: (2020)

Escherichia coli Nissle 1917 inhibits biofilm formation and mitigates virulence in Pseudomonas aeruginosa
por: Aljohani, Ahmad M., et al.
Publicado: (2023)

Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy
por: Tumas, Sarunas, et al.
Publicado: (2023)

Mutagenicity and genotoxicity of ClearTaste
por: Soni, B.K., et al.
Publicado: (2018)

Genotoxicity and Mutagenicity of Inosine Pranobex
por: Tobólska, Sylwia, et al.
Publicado: (2018)

Functional investigation of the chromosomal ccdAB and hipAB operon in Escherichia coli Nissle 1917
por: Xu, Jun, et al.
Publicado: (2020)

Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917
por: Dusek, Otakar, et al.
Publicado: (2020)

E. coli Nissle 1917 modulates host glucose metabolism without directly acting on glucose
por: Chavkin, Theodore A., et al.
Publicado: (2021)

Engineered Escherichia coli Nissle 1917 with urate oxidase and an oxygen-recycling system for hyperuricemia treatment
por: Zhao, Rui, et al.
Publicado: (2022)

Efficient markerless integration of genes in the chromosome of probiotic E. coli Nissle 1917 by bacterial conjugation
por: Seco, Elena M., et al.
Publicado: (2021)

Antibacterial MccM as the Major Microcin in Escherichia coli Nissle 1917 against Pathogenic Enterobacteria
por: Ma, Yi, et al.
Publicado: (2023)

The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice
por: Secher, Thomas, et al.
Publicado: (2018)

Erratum for Wallenstein et al., “ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli”
por: Wallenstein, Alexander, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_14ovrg8dsq163urtn7hrqmogd5