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Shigella-Specific Immune Profiles Induced after Parenteral Immunization or Oral Challenge with Either Shigella flexneri 2a or Shigella sonnei

Shigella spp. are a leading cause of diarrhea-associated global morbidity and mortality. Development and widespread implementation of an efficacious vaccine remain the best option to reduce Shigella-specific morbidity. Unfortunately, the lack of a well-defined correlate of protection for shigellosis...

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Detalles Bibliográficos
Autores principales: Clarkson, Kristen A., Porter, Chad K., Talaat, Kawsar R., Frenck, Robert W., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Kaminski, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386581/
https://www.ncbi.nlm.nih.gov/pubmed/34259559
http://dx.doi.org/10.1128/mSphere.00122-21