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Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging

Spermidine is a natural polyamine, central to cellular homeostasis and growth, that promotes macroautophagy/autophagy. The polyamine pathway is highly conserved from bacteria to mammals and spermidine (prominently found in some kinds of aged cheese, wheat germs, nuts, soybeans, and fermented product...

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Detalles Bibliográficos
Autores principales: Hofer, Sebastian J., Liang, YongTian, Zimmermann, Andreas, Schroeder, Sabrina, Dengjel, Jörn, Kroemer, Guido, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386697/
https://www.ncbi.nlm.nih.gov/pubmed/34105442
http://dx.doi.org/10.1080/15548627.2021.1933299