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Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging
Spermidine is a natural polyamine, central to cellular homeostasis and growth, that promotes macroautophagy/autophagy. The polyamine pathway is highly conserved from bacteria to mammals and spermidine (prominently found in some kinds of aged cheese, wheat germs, nuts, soybeans, and fermented product...
Autores principales: | Hofer, Sebastian J., Liang, YongTian, Zimmermann, Andreas, Schroeder, Sabrina, Dengjel, Jörn, Kroemer, Guido, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386697/ https://www.ncbi.nlm.nih.gov/pubmed/34105442 http://dx.doi.org/10.1080/15548627.2021.1933299 |
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