Predictors of Nonseroconversion after SARS-CoV-2 Infection

Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads...

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Detalles Bibliográficos
Autores principales: Liu, Weimin, Russell, Ronnie M., Bibollet-Ruche, Frederic, Skelly, Ashwin N., Sherrill-Mix, Scott, Freeman, Drew A., Stoltz, Regina, Lindemuth, Emily, Lee, Fang-Hua, Sterrett, Sarah, Bar, Katharine J., Erdmann, Nathaniel, Gouma, Sigrid, Hensley, Scott E., Ketas, Thomas, Cupo, Albert, Cruz Portillo, Victor M., Moore, John P., Bieniasz, Paul D., Hatziioannou, Theodora, Massey, Greer, Minyard, Mary-Beth, Saag, Michael S., Davis, Randall S., Shaw, George M., Britt, William J., Leal, Sixto M., Goepfert, Paul, Hahn, Beatrice H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386781/
https://www.ncbi.nlm.nih.gov/pubmed/34193339
http://dx.doi.org/10.3201/eid2709.211042
Descripción
Sumario:Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response.

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