Predictors of Nonseroconversion after SARS-CoV-2 Infection

Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads...

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Autores principales: Liu, Weimin, Russell, Ronnie M., Bibollet-Ruche, Frederic, Skelly, Ashwin N., Sherrill-Mix, Scott, Freeman, Drew A., Stoltz, Regina, Lindemuth, Emily, Lee, Fang-Hua, Sterrett, Sarah, Bar, Katharine J., Erdmann, Nathaniel, Gouma, Sigrid, Hensley, Scott E., Ketas, Thomas, Cupo, Albert, Cruz Portillo, Victor M., Moore, John P., Bieniasz, Paul D., Hatziioannou, Theodora, Massey, Greer, Minyard, Mary-Beth, Saag, Michael S., Davis, Randall S., Shaw, George M., Britt, William J., Leal, Sixto M., Goepfert, Paul, Hahn, Beatrice H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386781/
https://www.ncbi.nlm.nih.gov/pubmed/34193339
http://dx.doi.org/10.3201/eid2709.211042
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author Liu, Weimin
Russell, Ronnie M.
Bibollet-Ruche, Frederic
Skelly, Ashwin N.
Sherrill-Mix, Scott
Freeman, Drew A.
Stoltz, Regina
Lindemuth, Emily
Lee, Fang-Hua
Sterrett, Sarah
Bar, Katharine J.
Erdmann, Nathaniel
Gouma, Sigrid
Hensley, Scott E.
Ketas, Thomas
Cupo, Albert
Cruz Portillo, Victor M.
Moore, John P.
Bieniasz, Paul D.
Hatziioannou, Theodora
Massey, Greer
Minyard, Mary-Beth
Saag, Michael S.
Davis, Randall S.
Shaw, George M.
Britt, William J.
Leal, Sixto M.
Goepfert, Paul
Hahn, Beatrice H.
author_facet Liu, Weimin
Russell, Ronnie M.
Bibollet-Ruche, Frederic
Skelly, Ashwin N.
Sherrill-Mix, Scott
Freeman, Drew A.
Stoltz, Regina
Lindemuth, Emily
Lee, Fang-Hua
Sterrett, Sarah
Bar, Katharine J.
Erdmann, Nathaniel
Gouma, Sigrid
Hensley, Scott E.
Ketas, Thomas
Cupo, Albert
Cruz Portillo, Victor M.
Moore, John P.
Bieniasz, Paul D.
Hatziioannou, Theodora
Massey, Greer
Minyard, Mary-Beth
Saag, Michael S.
Davis, Randall S.
Shaw, George M.
Britt, William J.
Leal, Sixto M.
Goepfert, Paul
Hahn, Beatrice H.
author_sort Liu, Weimin
collection PubMed
description Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response.
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spelling pubmed-83867812021-09-04 Predictors of Nonseroconversion after SARS-CoV-2 Infection Liu, Weimin Russell, Ronnie M. Bibollet-Ruche, Frederic Skelly, Ashwin N. Sherrill-Mix, Scott Freeman, Drew A. Stoltz, Regina Lindemuth, Emily Lee, Fang-Hua Sterrett, Sarah Bar, Katharine J. Erdmann, Nathaniel Gouma, Sigrid Hensley, Scott E. Ketas, Thomas Cupo, Albert Cruz Portillo, Victor M. Moore, John P. Bieniasz, Paul D. Hatziioannou, Theodora Massey, Greer Minyard, Mary-Beth Saag, Michael S. Davis, Randall S. Shaw, George M. Britt, William J. Leal, Sixto M. Goepfert, Paul Hahn, Beatrice H. Emerg Infect Dis Dispatch Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response. Centers for Disease Control and Prevention 2021-09 /pmc/articles/PMC8386781/ /pubmed/34193339 http://dx.doi.org/10.3201/eid2709.211042 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Liu, Weimin
Russell, Ronnie M.
Bibollet-Ruche, Frederic
Skelly, Ashwin N.
Sherrill-Mix, Scott
Freeman, Drew A.
Stoltz, Regina
Lindemuth, Emily
Lee, Fang-Hua
Sterrett, Sarah
Bar, Katharine J.
Erdmann, Nathaniel
Gouma, Sigrid
Hensley, Scott E.
Ketas, Thomas
Cupo, Albert
Cruz Portillo, Victor M.
Moore, John P.
Bieniasz, Paul D.
Hatziioannou, Theodora
Massey, Greer
Minyard, Mary-Beth
Saag, Michael S.
Davis, Randall S.
Shaw, George M.
Britt, William J.
Leal, Sixto M.
Goepfert, Paul
Hahn, Beatrice H.
Predictors of Nonseroconversion after SARS-CoV-2 Infection
title Predictors of Nonseroconversion after SARS-CoV-2 Infection
title_full Predictors of Nonseroconversion after SARS-CoV-2 Infection
title_fullStr Predictors of Nonseroconversion after SARS-CoV-2 Infection
title_full_unstemmed Predictors of Nonseroconversion after SARS-CoV-2 Infection
title_short Predictors of Nonseroconversion after SARS-CoV-2 Infection
title_sort predictors of nonseroconversion after sars-cov-2 infection
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386781/
https://www.ncbi.nlm.nih.gov/pubmed/34193339
http://dx.doi.org/10.3201/eid2709.211042
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