Cargando…

The gut microbiome in sickle cell disease: Characterization and potential implications

BACKGROUND: Sickle Cell Disease (SCD) is an inherited blood disorder that leads to hemolytic anemia, pain, organ damage and early mortality. It is characterized by polymerized deoxygenated hemoglobin, rigid sickle red blood cells and vaso-occlusive crises (VOC). Recurrent hypoxia-reperfusion injury...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brim, Hassan, Taylor, James, Abbas, Muneer, Vilmenay, Kimberly, Daremipouran, Mohammad, Varma, Sudhir, Lee, Edward, Pace, Betty, Song-Naba, Waogwende L., Gupta, Kalpna, Nekhai, Sergei, O’Neil, Patricia, Ashktorab, Hassan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386827/ https://www.ncbi.nlm.nih.gov/pubmed/34432825 http://dx.doi.org/10.1371/journal.pone.0255956

Ejemplares similares

Distinct Genetic Alterations in Colorectal Cancer
por: Ashktorab, Hassan, et al.
Publicado: (2010)

Editorial to the Special Issue ‘Nutritional Intervention in Digestive Diseases in the Era of Nutraceuticals, Nutrigenomics and Microbiomics’
por: Ashktorab, Hassan, et al.
Publicado: (2023)

Microbiomic and Metabolomic Analyses Unveil the Protective Effect of Saffron in a Mouse Colitis Model
por: Singh, Gulshan, et al.
Publicado: (2023)

Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?
por: Ahmad, Sami, et al.
Publicado: (2022)

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia
por: Ashktorab, Hassan, et al.
Publicado: (2017)

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer
por: Ashktorab, Hassan, et al.
Publicado: (2016)

A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation
por: Brim, Hassan, et al.
Publicado: (2017)

Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia
por: Ashktorab, Hassan, et al.
Publicado: (2019)

Determination of distinctive hypomethylated genes in African American colorectal neoplastic lesions
por: Ashktorab, Hassan, et al.
Publicado: (2020)

Gastrointestinal manifestations and SARS-CoV-2 infection
por: Pizuorno, Antonio, et al.
Publicado: (2021)

Saffron, Its Active Components, and Their Association with DNA and Histone Modification: A Narrative Review of Current Knowledge
por: Rashid, Mudasir, et al.
Publicado: (2022)

Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Microbiome Analysis of Stool Samples from African Americans with Colon Polyps
por: Brim, Hassan, et al.
Publicado: (2013)

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice
por: Banskota, Suhrid, et al.
Publicado: (2021)

Metagenomics Approaches to Investigate the Neonatal Gut Microbiome
por: Boudar, Zakia, et al.
Publicado: (2022)

COVID-19 Pediatric Patients: Gastrointestinal Symptoms, Presentations, and Disparities by Race/Ethnicity in a Large, Multicenter US Study
por: Ashktorab, Yusuf, et al.
Publicado: (2021)

Pediatric COVID-19 and Gastrointestinal Symptoms in Africa
por: Brim, Anas, et al.
Publicado: (2021)

Fr093 COVID-19 PEDIATRIC PATIENTS IN THE UNITED STATES; AFRICAN AMERICAN AND HISPANIC AMONG MOST HOSPITALIZED PATIENTS WITH PERSISTENT GI MANIFESTATIONS
por: Ashktorab, Yusuf, et al.
Publicado: (2021)

Induction of Hepcidin Expression in the Renal Cortex of Sickle Cell Disease Mice
por: Ahmad, Asrar, et al.
Publicado: (2023)

SLC5A8 Gene, A Transporter of Butyrate: A Gut Flora Metabolite, Is Frequently Methylated in African American Colon Adenomas
por: Brim, Hassan, et al.
Publicado: (2011)

Elevated Liver Enzymes, Ferritin, C-reactive Protein, D-dimer, and Age Are Predictive Markers of Outcomes Among African American and Hispanic Patients With Coronavirus Disease 2019
por: Ashktorab, Hassan, et al.
Publicado: (2021)

COVID-19 in Latin America: Symptoms, Morbidities, and Gastrointestinal Manifestations
por: Ashktorab, Hassan, et al.
Publicado: (2021)

Predictors of Mortality in Hospitalized African American Covid-19 Cancer Patients
por: Challa, Suryanarayana Reddy, et al.
Publicado: (2022)

Gene expression changes in sickle cell reticulocytes and their clinical associations
por: Zhang, Xu, et al.
Publicado: (2023)

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk
por: Ashktorab, Hassan, et al.
Publicado: (2016)

Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions
por: Shokrani, Babak, et al.
Publicado: (2020)

PIWI interacting RNAs perspectives: a new avenues in future cancer investigations
por: Mokarram, Pooneh, et al.
Publicado: (2021)

Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells with Mismatch Repair Deficiency and Microsatellite Instability
por: Amin, Amr, et al.
Publicado: (2021)

Publisher Correction: Gene expression changes in sickle cell reticulocytes and their clinical associations
por: Zhang, Xu, et al.
Publicado: (2023)

Use of multiple urinary biomarkers for the early detection of chronic kidney disease in sickle cell anemia
por: Castro-Sesquen, Yagahira E., et al.
Publicado: (2023)

Lymph nodes’ evaluation in relation to colorectal cancer staging among African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2015)

Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia
por: Brim, Hassan, et al.
Publicado: (2018)

Exploring the Incidence and Associated Risk Factors of Barrett’s Esophagus in African Americans: A Retrospective Study
por: Ashktorab, Hassan, et al.
Publicado: (2023)

Morphine for the Treatment of Pain in Sickle Cell Disease
por: Gupta, Mihir, et al.
Publicado: (2015)

A new era dawns on sickle cell disease in India
por: Kishore, R. R., et al.
Publicado: (2023)

Soluble urokinase-type plasminogen activator receptor in sickle cell disease–associated chronic kidney disease
por: Afangbedji, Nowah, et al.
Publicado: (2022)

Atrial Fibrillation and Colonic Neoplasia in African Americans
por: Nouraie, Mehdi, et al.
Publicado: (2015)

Adiponectin, Leptin, IGF-1, and Tumor Necrosis Factor Alpha As Potential Serum Biomarkers for Non-Invasive Diagnosis of Colorectal Adenoma in African Americans
por: Ashktorab, Hassan, et al.
Publicado: (2018)

GPNMB methylation: a new marker of potentially carcinogenic colon lesions
por: Ashktorab, Hassan, et al.
Publicado: (2018)

COVID-19 and gastrointestinal symptoms in Mexico, a systematic review: does location matter?
por: Pizuorno, Antonio, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m1glhs36via59i7765kpmojees