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Nuclear translocation of MTL5 from cytoplasm requires its direct interaction with LIN9 and is essential for male meiosis and fertility

Meiosis is essential for the generation of gametes and sexual reproduction, yet the factors and underlying mechanisms regulating meiotic progression remain largely unknown. Here, we showed that MTL5 translocates into nuclei of spermatocytes during zygotene-pachytene transition and ensures meiosis ad...

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Detalles Bibliográficos
Autores principales: Zhang, Xingxia, Li, Ming, Jiang, Xiaohua, Ma, Hui, Fan, Suixing, Li, Yang, Yu, Changping, Xu, Jianze, Khan, Ranjha, Jiang, Hanwei, Shi, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386835/
https://www.ncbi.nlm.nih.gov/pubmed/34388164
http://dx.doi.org/10.1371/journal.pgen.1009753

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