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Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART

HIV-1 disrupts the host epigenetic landscape with consequences for disease pathogenesis, viral persistence, and HIV-associated comorbidities. Here, we examined how soon after infection HIV-associated epigenetic changes may occur in blood and whether early initiation of antiretroviral therapy (ART) i...

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Detalles Bibliográficos
Autores principales:	Corley, Michael J., Sacdalan, Carlo, Pang, Alina P. S., Chomchey, Nitiya, Ratnaratorn, Nisakorn, Valcour, Victor, Kroon, Eugene, Cho, Kyu S., Belden, Andrew C., Colby, Donn, Robb, Merlin, Hsu, Denise, Spudich, Serena, Paul, Robert, Vasan, Sandhya, Ndhlovu, Lishomwa C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386872/ https://www.ncbi.nlm.nih.gov/pubmed/34388205 http://dx.doi.org/10.1371/journal.ppat.1009785

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