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Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation

The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic role in safeguarding DNA replication forks. Using DNA replication reactions reconstituted with purified proteins, we show Rad53 phosphorylatio...

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Detalles Bibliográficos
Autores principales:	McClure, Allison W, Diffley, John FX
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387023/ https://www.ncbi.nlm.nih.gov/pubmed/34387546 http://dx.doi.org/10.7554/eLife.69726

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