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Multiplex assessment of SARS-CoV-2 antibodies improves assay sensitivity and correlation with neutralizing antibodies

OBJECTIVES: Detection of antibodies to multiple SARS-CoV-2 antigens in a single assay could increase diagnostic accuracy, differentiate vaccination from natural disease, and aid in retrospective exposure determination. Correlation of binding antibody assessment in clinical assays with neutralizing a...

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Detalles Bibliográficos
Autores principales: Cook, Nathan, Xu, Lingqing, Hegazy, Shaymaa, Wheeler, Bradley J., Anderson, Adam R., Critelli, Nancy, Yost, Mary, McElroy, Anita K., Shurin, Michael R., Wheeler, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Canadian Society of Clinical Chemists. Published by Elsevier Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387133/
https://www.ncbi.nlm.nih.gov/pubmed/34453893
http://dx.doi.org/10.1016/j.clinbiochem.2021.08.006