Thymic hyperplasia after mRNA based Covid-19 vaccination

Reactive lymphadenopathy with increased 18F-Fluordeoxyglucose uptake in positron emission tomography/computed tomography scans is known after mRNA vaccination (BNT162B2, mRNA-1273) against severe acute respiratory syndrome coronavirus type 2. Besides this, increased 18F-Fluordeoxyglucose uptake in t...

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Detalles Bibliográficos
Autores principales: von Tresckow, Julia, von Tresckow, Bastian, Reinhardt, H. Christian, Herrmann, Ken, Berliner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387216/
https://www.ncbi.nlm.nih.gov/pubmed/34462647
http://dx.doi.org/10.1016/j.radcr.2021.08.050
Descripción
Sumario:Reactive lymphadenopathy with increased 18F-Fluordeoxyglucose uptake in positron emission tomography/computed tomography scans is known after mRNA vaccination (BNT162B2, mRNA-1273) against severe acute respiratory syndrome coronavirus type 2. Besides this, increased 18F-Fluordeoxyglucose uptake in the thymus might occur after mRNA vaccination as shown in our case of a young patient with mantle cell lymphoma. Especially in patients with lymphoma but also in other patients with cancer it is critical to distinguish between immune responses and involvement of the disease to avoid inadequate treatment decisions.

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