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Optimising PHBV biopolymer production in haloarchaea via CRISPRi-mediated redirection of carbon flux

The haloarchaeon Haloferax mediterranei is a potential strain for poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) production, yet the production yield and cost are the major obstacles hindering the use of this archaeal strain. Leveraging the endogenous type I-B CRISPR-Cas system in H. mediterran...

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Detalles Bibliográficos
Autores principales:	Lin, Lin, Chen, Junyu, Mitra, Ruchira, Gao, Quanxiu, Cheng, Feiyue, Xu, Tong, Zuo, Zhenqiang, Xiang, Hua, Han, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387396/ https://www.ncbi.nlm.nih.gov/pubmed/34433872 http://dx.doi.org/10.1038/s42003-021-02541-z

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