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Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study
This single-arm phase II study investigated the efficacy and safety of cabozantinib combined with nivolumab in metastatic triple-negative breast cancer (mTNBC). The primary endpoint was objective response rate (ORR) by RECIST 1.1. Biopsies at baseline and after cycle 1 were analyzed for tumor-infilt...
Autores principales: | Barroso-Sousa, Romualdo, Keenan, Tanya E., Li, Tianyu, Tayob, Nabihah, Trippa, Lorenzo, Pastorello, Ricardo G., Richardson III, Edward T., Dillon, Deborah, Amoozgar, Zohreh, Overmoyer, Beth, Schnitt, Stuart J., Winer, Eric P., Mittendorf, Elizabeth A., Van Allen, Eliezer, Duda, Dan G., Tolaney, Sara M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387440/ https://www.ncbi.nlm.nih.gov/pubmed/34433812 http://dx.doi.org/10.1038/s41523-021-00287-9 |
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