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GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays

Can one learn to diagnose COVID-19 under extreme minimal supervision? Since the outbreak of the novel COVID-19 there has been a rush for developing automatic techniques for expert-level disease identification on Chest X-ray data. In particular, the use of deep supervised learning has become the go-t...

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Autores principales: Aviles-Rivero, Angelica I., Sellars, Philip, Schönlieb, Carola-Bibiane, Papadakis, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387569/
https://www.ncbi.nlm.nih.gov/pubmed/34462610
http://dx.doi.org/10.1016/j.patcog.2021.108274
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author Aviles-Rivero, Angelica I.
Sellars, Philip
Schönlieb, Carola-Bibiane
Papadakis, Nicolas
author_facet Aviles-Rivero, Angelica I.
Sellars, Philip
Schönlieb, Carola-Bibiane
Papadakis, Nicolas
author_sort Aviles-Rivero, Angelica I.
collection PubMed
description Can one learn to diagnose COVID-19 under extreme minimal supervision? Since the outbreak of the novel COVID-19 there has been a rush for developing automatic techniques for expert-level disease identification on Chest X-ray data. In particular, the use of deep supervised learning has become the go-to paradigm. However, the performance of such models is heavily dependent on the availability of a large and representative labelled dataset. The creation of which is a heavily expensive and time consuming task, and especially imposes a great challenge for a novel disease. Semi-supervised learning has shown the ability to match the incredible performance of supervised models whilst requiring a small fraction of the labelled examples. This makes the semi supervised paradigm an attractive option for identifying COVID-19. In this work, we introduce a graph based deep semi-supervised framework for classifying COVID-19 from chest X-rays. Our framework introduces an optimisation model for graph diffusion that reinforces the natural relation among the tiny labelled set and the vast unlabelled data. We then connect the diffusion prediction output as pseudo-labels that are used in an iterative scheme in a deep net. We demonstrate, through our experiments, that our model is able to outperform the current leading supervised model with a tiny fraction of the labelled examples. Finally, we provide attention maps to accommodate the radiologist’s mental model, better fitting their perceptual and cognitive abilities. These visualisation aims to assist the radiologist in judging whether the diagnostic is correct or not, and in consequence to accelerate the decision.
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spelling pubmed-83875692021-08-26 GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays Aviles-Rivero, Angelica I. Sellars, Philip Schönlieb, Carola-Bibiane Papadakis, Nicolas Pattern Recognit Article Can one learn to diagnose COVID-19 under extreme minimal supervision? Since the outbreak of the novel COVID-19 there has been a rush for developing automatic techniques for expert-level disease identification on Chest X-ray data. In particular, the use of deep supervised learning has become the go-to paradigm. However, the performance of such models is heavily dependent on the availability of a large and representative labelled dataset. The creation of which is a heavily expensive and time consuming task, and especially imposes a great challenge for a novel disease. Semi-supervised learning has shown the ability to match the incredible performance of supervised models whilst requiring a small fraction of the labelled examples. This makes the semi supervised paradigm an attractive option for identifying COVID-19. In this work, we introduce a graph based deep semi-supervised framework for classifying COVID-19 from chest X-rays. Our framework introduces an optimisation model for graph diffusion that reinforces the natural relation among the tiny labelled set and the vast unlabelled data. We then connect the diffusion prediction output as pseudo-labels that are used in an iterative scheme in a deep net. We demonstrate, through our experiments, that our model is able to outperform the current leading supervised model with a tiny fraction of the labelled examples. Finally, we provide attention maps to accommodate the radiologist’s mental model, better fitting their perceptual and cognitive abilities. These visualisation aims to assist the radiologist in judging whether the diagnostic is correct or not, and in consequence to accelerate the decision. Elsevier Ltd. 2022-02 2021-08-26 /pmc/articles/PMC8387569/ /pubmed/34462610 http://dx.doi.org/10.1016/j.patcog.2021.108274 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Aviles-Rivero, Angelica I.
Sellars, Philip
Schönlieb, Carola-Bibiane
Papadakis, Nicolas
GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title_full GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title_fullStr GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title_full_unstemmed GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title_short GraphXCOVID: Explainable deep graph diffusion pseudo-Labelling for identifying COVID-19 on chest X-rays
title_sort graphxcovid: explainable deep graph diffusion pseudo-labelling for identifying covid-19 on chest x-rays
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387569/
https://www.ncbi.nlm.nih.gov/pubmed/34462610
http://dx.doi.org/10.1016/j.patcog.2021.108274
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