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Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats

PURPOSE: Avitinib is the first third-generation epithelial growth factor receptor (EGFR) inhibitor independently developed in China and is mainly used for treating non-small cell lung cancer. However, pharmacokinetic details are limited. This study explored the in vivo and in vitro effects of avitin...

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Detalles Bibliográficos
Autores principales:	Shi, Yong, Meng, Deru, Wang, Shuanghu, Geng, Peiwu, Xu, Tao, Zhou, Quan, Zhou, Yunfang, Li, Wanshu, Chen, Xugao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387736/ https://www.ncbi.nlm.nih.gov/pubmed/34456561 http://dx.doi.org/10.2147/DDDT.S323186

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