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Endocannabinoid activation of the TRPV1 ion channel is distinct from activation by capsaicin

Transient receptor potential vanilloid 1 (TRPV1) ion channel serves as the detector for noxious temperature above 42 °C, pungent chemicals like capsaicin, and acidic extracellular pH. This channel has also been shown to function as an ionotropic cannabinoid receptor. Despite the solving of high-reso...

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Detalles Bibliográficos
Autores principales: Li, Yanxin, Chen, Xiaoying, Nie, Yingying, Tian, Yuhua, Xiao, Xian, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387766/
https://www.ncbi.nlm.nih.gov/pubmed/34332978
http://dx.doi.org/10.1016/j.jbc.2021.101022

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