Cargando…
Endocannabinoid activation of the TRPV1 ion channel is distinct from activation by capsaicin
Transient receptor potential vanilloid 1 (TRPV1) ion channel serves as the detector for noxious temperature above 42 °C, pungent chemicals like capsaicin, and acidic extracellular pH. This channel has also been shown to function as an ionotropic cannabinoid receptor. Despite the solving of high-reso...
Autores principales: | Li, Yanxin, Chen, Xiaoying, Nie, Yingying, Tian, Yuhua, Xiao, Xian, Yang, Fan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387766/ https://www.ncbi.nlm.nih.gov/pubmed/34332978 http://dx.doi.org/10.1016/j.jbc.2021.101022 |
Ejemplares similares
-
Structural mechanism underlying capsaicin binding and activation of TRPV1 ion channel
por: Yang, Fan, et al.
Publicado: (2015) -
Understand spiciness: mechanism of TRPV1 channel activation by capsaicin
por: Yang, Fan, et al.
Publicado: (2017) -
Molecular mechanism underlying modulation of TRPV1 heat activation by polyols
por: Nie, Yingying, et al.
Publicado: (2021) -
The capsaicin binding affinity of wildtype and mutant TRPV1 ion channels
por: Li, Shisheng, et al.
Publicado: (2023) -
Capsaicin-Sensitive Sensory Nerves and the TRPV1 Ion Channel in Cardiac Physiology and Pathologies
por: Szabados, Tamara, et al.
Publicado: (2020)