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Repositioning of duloxetine to target pancreatic stellate cells

Pancreatic cancer cells (PCCs) are surrounded by an abundant stroma, which is produced by pancreatic stellate cells (PSCs). PSCs promote tumor cell proliferation and invasion. The objective of the current study was to identify compounds that suppress PSC activation. Gene expression profiles of cance...

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Detalles Bibliográficos
Autores principales: Sagara, Akiko, Nakata, Kohei, Matsumoto, Sokichi, Guan, Weiyu, Shinkawa, Tomohiko, Iwamoto, Chika, Ikenaga, Naoki, Ohuchida, Kenoki, Nakamura, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387862/
https://www.ncbi.nlm.nih.gov/pubmed/34466156
http://dx.doi.org/10.3892/ol.2021.13005