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Repositioning of duloxetine to target pancreatic stellate cells
Pancreatic cancer cells (PCCs) are surrounded by an abundant stroma, which is produced by pancreatic stellate cells (PSCs). PSCs promote tumor cell proliferation and invasion. The objective of the current study was to identify compounds that suppress PSC activation. Gene expression profiles of cance...
Autores principales: | Sagara, Akiko, Nakata, Kohei, Matsumoto, Sokichi, Guan, Weiyu, Shinkawa, Tomohiko, Iwamoto, Chika, Ikenaga, Naoki, Ohuchida, Kenoki, Nakamura, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387862/ https://www.ncbi.nlm.nih.gov/pubmed/34466156 http://dx.doi.org/10.3892/ol.2021.13005 |
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