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Identification of signalling pathways activated by Tyro3 that promote cell survival, proliferation and invasiveness in human cancer cells

Tyro3 is a member of the TAM subfamily of receptor tyrosine kinases alongside Axl and MerTK, which are activated by homologous ligands Gas6 and protein S. The TAMs activate signalling pathways that mediate diverse functions including cell survival, proliferation, phagocytosis and immune regulation,...

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Detalles Bibliográficos
Autores principales: Al Kafri, Nour, Hafizi, Sassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387907/
https://www.ncbi.nlm.nih.gov/pubmed/34471705
http://dx.doi.org/10.1016/j.bbrep.2021.101111